San Diego Chargers upset Indianapolis Colts, 26–17

The Chargers closed as 7.5-point underdogs and won outright.

It was the biggest of 1 NFL upset in 2005 Week 15, and the 10th-biggest of the 2005 season. San Diego Chargers pulled off 1 other upset in 2005.

San Diego Chargers’ other 2005 upsets

1. San Diego Chargers 41, New England Patriots 17

   Week 45.5-point underdogRecap
   Upset size5.5

More: San Diego Chargers upsets · Indianapolis Colts upsets · all Week 15 upsets · how upset size works