College football · NFLTuesday, October 13, 2026
The Upset Report
NFL · 2010 · Week 11 · Sunday, November 21, 2010

Buffalo Bills beat Cincinnati Bengals, 49–31

The Bills closed as 4-point underdogs and won outright. The betting market gave them a 34% chance.

Final49–31
Upset size4
Chance to win34%
Rank in 201037th of 47

It was the 2nd-biggest of 3 NFL upsets in 2010 Week 11, and the 37th-biggest of the 2010 season. Buffalo Bills pulled off 1 other upset in 2010.

Other NFL upsets in 2010 Week 11

  1. 7-point underdog26% to winOTRecap
    Upset size7
  2. 3.5-point underdog35% to winRecap
    Upset size3.5

Buffalo Bills’ other 2010 upsets

  1. Week 155.5-point underdog32% to winRecap
    Upset size5.5

More: Buffalo Bills upsets · Cincinnati Bengals upsets · all Week 11 upsets · how upset size works