College football · NFLTuesday, October 13, 2026
The Upset Report
NFL · 2016 · Week 3 · Sunday, September 25, 2016

Buffalo Bills beat Arizona Cardinals, 33–18

The Bills closed as 5-point underdogs and won outright. The betting market gave them a 33% chance.

Final33–18
Upset size5
Chance to win33%
Rank in 201620th of 49

It was the 2nd-biggest of 6 NFL upsets in 2016 Week 3, and the 20th-biggest of the 2016 season. Buffalo Bills pulled off 1 other upset in 2016.

Other NFL upsets in 2016 Week 3

  1. 6-point underdog30% to winRecap
    Upset size6
  2. 3.5-point underdog37% to winRecap
    Upset size3.5
  3. 3.5-point underdog38% to winRecap
    Upset size3.5
  4. 3.5-point underdog38% to winRecap
    Upset size3.5
  5. 3.5-point underdog36% to winRecap
    Upset size3.5

Buffalo Bills’ other 2016 upsets

  1. Week 43.5-point underdog39% to winRecap
    Upset size3.5

More: Buffalo Bills upsets · Arizona Cardinals upsets · all Week 3 upsets · how upset size works