College football · NFLTuesday, October 13, 2026
The Upset Report
NFL · 2021 · Week 10 · Sunday, November 14, 2021

Carolina Panthers upset Arizona Cardinals, 34–10

The Panthers closed as 7-point underdogs and won outright. The betting market gave them a 26% chance.

Final34–10
Upset size7
Chance to win26%
Rank in 202117th of 58

It was the 3rd-biggest of 4 NFL upsets in 2021 Week 10, and the 17th-biggest of the 2021 season. It was Carolina Panthers's only upset win of 2021.

Other NFL upsets in 2021 Week 10

  1. Washington Commanders 29, Tampa Bay Buccaneers 19
    10-point underdog21% to winRecap
    Upset size10
  2. Miami Dolphins 22, Baltimore Ravens 10
    8.5-point underdog23% to winRecap
    Upset size8.5
  3. San Francisco 49ers 31, Los Angeles Rams 10
    3.5-point underdog38% to winRecap
    Upset size3.5

More: Carolina Panthers upsets · Arizona Cardinals upsets · all Week 10 upsets · how upset size works