Holy Cross upsets Buffalo, 37–31
Holy Cross closed as a 6-point underdog and won outright.
Final37–31
Upset size6
Rank in 2022123rd of 215
It was the 13th-biggest of 19 upsets in 2022 Week 2, and the 123rd-biggest of the 2022 season. It was Holy Cross's only upset win of 2022.
Other upsets in 2022 Week 2
Marshall 26, 
No. 8 Notre Dame 21Upset size29.5
App State 17, 
No. 6 Texas A&M 14Upset size28
Georgia Southern 45, 
Nebraska 42Upset size23.5
Washington State 17, 
No. 19 Wisconsin 14Upset size21
Kansas 55, 
West Virginia 42Upset size14
More: Holy Cross upsets · Buffalo upsets · all Week 2 upsets · the 2022 season · how upset size works