West Virginia stuns No. 22 Houston, 45–35

West Virginia closed as a 12.5-point underdog and won outright. It was unranked West Virginia taking down the No. 22 team in the AP poll.

It was the 2nd-biggest of 17 upsets in 2025 Week 10, and the 20th-biggest of the 2025 season. West Virginia pulled off 1 other upset in 2025.

Other upsets in 2025 Week 10

1. Fresno State 30, Boise State 7

   17.5-point underdogRecap
   Upset size17.5
2. SMU 26, No. 10 Miami 20

   6.5-point underdogUnranked beat No. 10Recap
   Upset size14.5
3. NC State 48, No. 8 Georgia Tech 36

   4.5-point underdogUnranked beat No. 8Recap
   Upset size13.5
4. Kentucky 10, Auburn 3

   11.5-point underdogRecap
   Upset size11.5
5. Arizona State 24, Iowa State 19

   8.5-point underdogRecap
   Upset size8.5

West Virginia’s other 2025 upsets

1. West Virginia 31, Pittsburgh 24

   Week 36.5-point underdogRecap
   Upset size6.5

More: West Virginia upsets · Houston upsets · all Week 10 upsets · the 2025 season · how upset size works