Penn State edges No. 22 Purdue, 22–20
It was unranked Penn State taking down the No. 22 team in the AP poll.
Final22–20
Upset size2
Rank in 200040th of 56
It was the 6th-biggest of 8 upsets in 2000 Week 6, and the 40th-biggest of the 2000 season. It was Penn State's only upset win of 2000.
Other upsets in 2000 Week 6
Mississippi State 47, 
No. 3 Florida 35Upset size11.5
Oregon State 31, 
No. 8 USC 21Upset size9
LSU 38, 
No. 11 Tennessee 31Upset size7.5
No. 20 Oregon 23, 
No. 6 Washington 16Upset size7- Upset size4
More: Penn State upsets · Purdue upsets · all Week 6 upsets · the 2000 season · how upset size works