NFL · 2026 · Week 1 · Thursday, September 10, 2026 · Neutral site
San Francisco 49ers beat Los Angeles Rams, 27–7
The 49ers closed as 3.5-point underdogs and won outright. The betting market gave them a 34% chance.
Final27–7
Upset size3.5
Chance to win34%
Rank in 202616th of 16
It was the 2nd-biggest of 2 NFL upsets in 2026 Week 1, and the 16th-biggest of the 2026 season. It was San Francisco 49ers's only upset win of 2026.
Other NFL upsets in 2026 Week 1
- Upset size8.5
More: San Francisco 49ers upsets · Los Angeles Rams upsets · all Week 1 upsets · how upset size works