Arizona Cardinals upset Los Angeles Chargers, 26–14

The Cardinals closed as 8.5-point underdogs and won outright. The betting market gave them a 21% chance.

All 2026 NFL Week 1 upsets, biggest first

An NFL upset is an underdog getting 3.5 or more points on the closing line winning outright. Upset size is the points it overcame. How it’s scored

1. Arizona Cardinals 26, Los Angeles Chargers 14

   8.5-point underdog21% to winRecap
   Upset size8.5
2. San Francisco 49ers 27, Los Angeles Rams 7

   3.5-point underdog34% to winRecap
   Upset size3.5