Duke upsets No. 16 Virginia, 27–20

Duke closed as a 3.5-point underdog and won outright. It was unranked Duke taking down the No. 16 team in the AP poll.

All 2025 Week 15 upsets, biggest first

Upset size is the points the winner overcame on the closing line plus a bonus for beating a ranked team. How it’s scored

1. Duke 27, No. 16 Virginia 20

   3.5-point underdogUnranked beat No. 16Recap
   Upset size8.5
2. No. 2 Indiana 13, No. 1 Ohio State 10

   5.5-point underdogNo. 2 beat No. 1Recap
   Upset size6
3. No. 21 Tulane 34, No. 20 North Texas 21

   No. 21 beat No. 20Recap
   Upset size3