No. 25 Missouri stuns No. 8 Florida, 45–17

Missouri closed as a 5.5-point underdog and won outright. No. 25 beat No. 8 in the AP poll.

All 2026 Week 5 upsets, biggest first

Upset size is the points the winner overcame on the closing line plus a bonus for beating a ranked team. How it’s scored

1. No. 25 Missouri 45, No. 8 Florida 17

   5.5-point underdogNo. 25 beat No. 8Recap
   Upset size14
2. Bowling Green 24, Miami (OH) 20

   10.5-point underdogRecap
   Upset size10.5
3. San Diego State 31, Texas State 29

   10-point underdogRecap
   Upset size10
4. Purdue 24, Illinois 17

   9.5-point underdogRecap
   Upset size9.5
5. Minnesota 20, Michigan 14

   6.5-point underdogRecap
   Upset size6.5
6. Temple 17, South Florida 13

   5.5-point underdogRecap
   Upset size5.5
7. Eastern Michigan 38, Massachusetts 14

   5.5-point underdogRecap
   Upset size5.5
8. NC State 31, Louisville 28

   5.5-point underdogRecap
   Upset size5.5
9. Baylor 55, Arizona State 19

   3.5-point underdogRecap
   Upset size3.5
10. Northwestern 34, Penn State 13

    3-point underdogRecap
    Upset size3