Southern Miss stuns Louisiana Tech, 35–19

Southern Miss closed as a 15.5-point underdog and won outright.

All 2021 Week 12 upsets, biggest first

Upset size is the points the winner overcame on the closing line plus a bonus for beating a ranked team. How it’s scored

1. Southern Miss 35, Louisiana Tech 19

   15.5-point underdogRecap
   Upset size15.5
2. No. 24 Utah 38, No. 4 Oregon 7

   No. 24 beat No. 4Recap
   Upset size10
3. Missouri 24, Florida 23

   9-point underdogRecap
   Upset size9
4. South Carolina 21, Auburn 17

   7-point underdogRecap
   Upset size7
5. Clemson 48, No. 13 Wake Forest 27

   Unranked beat No. 13Recap
   Upset size6.5
6. Colorado 20, Washington 17

   6.5-point underdogRecap
   Upset size6.5
7. Eastern Michigan 22, Western Michigan 21

   6-point underdogRecap
   Upset size6
8. Wyoming 44, Utah State 17

   5.5-point underdogRecap
   Upset size5.5
9. No. 22 Louisiana 42, Liberty 14

   4.5-point underdogRecap
   Upset size4.5
10. Old Dominion 24, Middle Tennessee 17

    3-point underdogRecap
    Upset size3
11. Florida State 26, Boston College 23

    3-point underdogRecap
    Upset size3
12. Oregon State 24, Arizona State 10

    3-point underdogRecap
    Upset size3
13. Hawai'i 50, Colorado State 45

    3-point underdogRecap
    Upset size3